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ruview-model-training
【效率与协作】Train RuView models — camera-free WiFlow pose (10 sensor signals, no labels), camera-supervised pose (MediaPipe + ESP32 CSI → 92.9% PCK@20, ADR-079), RuVector contrastive embeddings (AETHER, ADR-024), domain generalization (MERIDIAN, ADR-027), local SNN environment adaptation, plus GPU training on GCloud and Hugging Face publishing. Use when building…
orchestration
【效率与协作】Coordinate supervised Orca workers: threaded messages, blocking ask/reply, task dispatch, worker_done/escalation waits, task DAGs, decision gates, coordinator loops, and decomposing work across agents. Use `orca-cli` for full ownership handoffs — "hand off", "handoff", "handover", "give this to another agent", "another worktree" — unless asked to sup…
scikit-learn
【文档与办公】Supports machine learning in Python with scikit-learn. Applies when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing …
torchdrug
【数据与研究】Builds and troubleshoots TorchDrug 0.2.1 workflows for molecular graphs, property prediction, self-supervised pretraining, molecule generation, retrosynthesis, protein representation learning, and knowledge graph reasoning. Use when code imports torchdrug or needs its datasets, models, tasks, or Engine.
umap-learn
【效率与协作】Applies UMAP-learn to nonlinear dimensionality reduction, 2D/3D embeddings, clustering preprocessing, supervised or semi-supervised UMAP, DensMAP, AlignedUMAP, and Parametric UMAP workflows.
anti-sleep
【效率与协作】Keep a Mac awake with caffeinate during long builds, downloads, or supervised automation runs.
yann-lecun-tecnico
【开发与工程】Sub-skill técnica de Yann LeCun. Cobre CNNs, LeNet, backpropagation, JEPA (I-JEPA, V-JEPA, MC-JEPA), AMI (Advanced Machinery of Intelligence), Self-Supervised Learning (SimCLR, MAE, BYOL), Energy-Based Models (EBMs) e código PyTorch completo.
constitutional-ai
【效率与协作】Anthropic's method for training harmless AI through self-improvement. Two-phase approach - supervised learning with self-critique/revision, then RLAIF (RL from AI Feedback). Use for safety alignment, reducing harmful outputs without human labels. Powers Claude's safety system.
scvi-tools
【开发与工程】Probabilistic single-cell RNA-seq with scvi-tools — scVI for a batch-corrected latent space, scANVI for semi-supervised label transfer, and Bayesian differential expression. Reach for this skill to integrate scRNA-seq batches, embed cells for clustering, transfer annotations from a reference onto a query, or score differentially expressed genes per c…
finetuning
【部署与运维】Fine-tune models on Microsoft Foundry using SFT (supervised), DPO (preference), or RFT (reinforcement with graders). Covers dataset preparation, training job submission, deployment, and evaluation. USE FOR: fine-tune, SFT, DPO, RFT, training data, grader, distillation, fine-tuned model, training job, large file upload, calibrate grader, deploy fine-t…
tooluniverse-scvi-tools
【数据与研究】Deep learning for single-cell omics using scvi-tools — probabilistic (VAE-based) batch correction and integration with scVI, semi-supervised integration and label transfer with scANVI, CITE-seq RNA+protein joint modeling with totalVI, scATAC-seq analysis with PeakVI, multiome RNA+ATAC joint modeling with MultiVI, spatial transcriptomics cell-type dec…
tooluniverse-scvi-tools
【数据与研究】Deep learning for single-cell omics using scvi-tools — probabilistic (VAE-based) batch correction and integration with scVI, semi-supervised integration and label transfer with scANVI, CITE-seq RNA+protein joint modeling with totalVI, scATAC-seq analysis with PeakVI, multiome RNA+ATAC joint modeling with MultiVI, spatial transcriptomics cell-type dec…
bio-crispr-screens-copy-number-correction
【数据与研究】Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the gene-independent DNA-damage / G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + g…
bio-flow-cytometry-clustering-phenotyping
【设计与创意】Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE for visualization. Covers the type-vs-state marker distinction (cluster on lineage, test state within clusters), over-provision-then-metacluster, the Weber-Robinson benchmark, seed de…
bio-immunoinformatics-tcr-epitope-binding
【数据与研究】Infer or annotate TCR antigen specificity by unsupervised clustering (TCRdist/tcrdist3, GLIPH2, clusTCR, GIANA) and database lookup (VDJdb, IEDB, McPAS-TCR), and rank candidates with supervised predictors (ERGO-II, NetTCR-2.x, pMTnet) under explicit caveats. Encodes the central truth that general TCR-epitope prediction for UNSEEN epitopes essentially…
bio-metabolomics-statistical-analysis
【设计与创意】Decision-grade statistical analysis for metabolomics intensity tables. Covers transformation and scaling (Pareto vs unit-variance as a hidden hypothesis), unsupervised structure (PCA/HCA for QC), permutation-validated PLS-DA/OPLS-DA (R2 vs Q2, double CV, VIP as heuristic), univariate testing (Welch/Mann-Whitney/ANOVA/LMM with covariate adjustment), a…
bio-multi-omics-mixomics-analysis
【设计与创意】Builds supervised and unsupervised multivariate integration across bulk omics blocks with mixOmics - sPLS for sparse pairwise correlation, DIABLO (block.splsda) for a multi-block discriminant signature, rCCA for regularized canonical correlation, and MINT for multi-study integration. Covers why these projection methods maximize covariance or correlat…
bio-multi-omics-mofa-integration
【设计与创意】Discovers shared and view-specific latent factors across bulk multi-omics blocks (RNA-seq, proteomics, methylation) on a common sample axis with MOFA2's unsupervised Bayesian group factor model, then attributes per-view variance explained and interprets signed factor weights. Covers why a factor is an unsupervised axis of variance and not a pathway, …