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bio-hi-c-analysis-hic-differential
【数据与研究】Compares Hi-C contact maps between conditions across the right scale -- differential bin-pair contacts (multiHiCcompare, diffHic), differential A/B compartments (dcHiC), differential TAD boundaries (delta insulation), and differential loops (diffloop, DiffHiChIP) -- with distance-stratified between-sample normalization, replicate-aware NB-GLM FDR, Hi…
bio-hi-c-analysis-tad-detection
【设计与创意】Detects TAD boundaries from balanced Hi-C contact matrices via the diamond-window insulation score (cooltools insulation) and HiCExplorer hicFindTADs, returning a continuous log2 insulation track, valley-prominence boundary_strength, and Li/Otsu-thresholded is_boundary flags across a list of window sizes. Covers the multi-scale window sweep (sub-TAD …
acoustic-design
【设计与创意】Acoustic design for buildings: sound insulation between spaces (airborne and impact), room acoustics and reverberation control, environmental noise intrusion, noise and vibration from building services, and acoustic design strategies for residential, commercial, educational, healthcare, performance, and worship building types.
bio-hi-c-analysis-tad-detection
【数据与研究】Call topologically associating domains (TADs) from Hi-C data using insulation score, HiCExplorer, and other methods. Identify domain boundaries and hierarchical domain structure. Use when calling TADs from Hi-C insulation scores.
cold_weather_outfit_layering_generator
【效率与协作】Generate or categorize clothing items for a cold/winter environment using a specific 5-layer system (Underwear, Base, Middle, Insulation, Outer) and a numbered list format, while adhering to the character's aesthetic.