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THE SKILLS DIRECTORY

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35 项技能disorder

bio-structural-biology-alphafold-predictions

bio-structural-biology-alphafold-predictions

【数据与研究】Retrieves and interprets AlphaFold Protein Structure Database (AFDB) models by UniProt accession, reading pLDDT and PAE confidence correctly. Use when treating pLDDT as PER-RESIDUE confidence (not global accuracy) and recognizing a long low-pLDDT stretch as an intrinsically disordered region rather than a modeling error; reading PAE to segment confid…

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bio-structural-biology-structure-navigation

bio-structural-biology-structure-navigation

【开发与工程】Navigate the Bio.PDB SMCRA hierarchy (Structure-Model-Chain-Residue-Atom) safely, surfacing the heterogeneity it hides by default. Use when deciding how to handle altloc/DisorderedAtom conformers before a distance or RMSD, indexing residues insertion-code-safe with the full (hetflag, resseq, icode) tuple, choosing the ATOM/observed vs SEQRES/canonica…

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