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experimental-design
【设计与创意】Designs experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. Use whenever someone is planning a study, asks how to assign subjects/samples to groups, mentions randomization, blocking, stratification, controls, factorial or fractional-factorial …
antigravity-skill-orchestrator
【开发与工程】A meta-skill that understands task requirements, dynamically selects appropriate skills, tracks successful skill combinations using agent-memory-mcp, and prevents skill overuse for simple tasks.
selenium-skill
【开发与工程】Generates production-grade Selenium WebDriver automation scripts and tests in Java, Python, JavaScript, C#, Ruby, or PHP. Supports local execution and TestMu AI cloud with 3000+ browser/OS combinations.
cross-platform-test-matrix
【开发与工程】Generate CI test matrix for Windows, macOS, and Linux combinations
fea-structural-engine
【数据与研究】Finite Element Analysis skill for linear and nonlinear structural analysis, modal analysis, and load combination processing
load-combination-generator
【设计与创意】Load combination generation skill per ASCE 7 and AASHTO for ASD and LRFD design methods
tooluniverse-drug-synergy
【数据与研究】Drug-combination synergy analysis — quantify whether two drugs together are synergistic, additive, or antagonistic using the standard reference models (Bliss independence, HSA / highest single agent, Loewe additivity, ZIP, and the Chou-Talalay Combination Index). Use when you have measured single-drug and combination effects (inhibition/viability) an…
tooluniverse-drug-mechanism-research
【设计与创意】Trace drug mechanism of action — primary target → downstream signaling → pathway perturbation → tissue/organ effect → clinical outcome. Uses DrugBank, ChEMBL, KEGG, Reactome, STRING. Use for understanding how a drug works, identifying off-target effects, mechanism-based combination therapy design, and writing mechanism sections of reports.
tooluniverse-drug-synergy
【数据与研究】Drug-combination synergy analysis — quantify whether two drugs together are synergistic, additive, or antagonistic using the standard reference models (Bliss independence, HSA / highest single agent, Loewe additivity, ZIP, and the Chou-Talalay Combination Index). Use when you have measured single-drug and combination effects (inhibition/viability) an…
tooluniverse-drug-mechanism-research
【设计与创意】Trace drug mechanism of action — primary target → downstream signaling → pathway perturbation → tissue/organ effect → clinical outcome. Uses DrugBank, ChEMBL, KEGG, Reactome, STRING. Use for understanding how a drug works, identifying off-target effects, mechanism-based combination therapy design, and writing mechanism sections of reports.
tooluniverse-drug-synergy
【数据与研究】Drug-combination synergy analysis — quantify whether two drugs together are synergistic, additive, or antagonistic using the standard reference models (Bliss independence, HSA / highest single agent, Loewe additivity, ZIP, and the Chou-Talalay Combination Index). Use when you have measured single-drug and combination effects (inhibition/viability) an…
bio-copy-number-hrd-scoring
【效率与协作】Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical …
bio-entrez-fetch
【文档与办公】Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary). Use when downloading sequences, fetching GenBank/GenPept records, getting document summaries, parsing nested XML, navigating GI deprecation, choosing between rettype+retmode combinations, and parsing into Biopython SeqRecord/SwissProt objects. Covers nucleotide, prote…
bio-population-genetics-linkage-disequilibrium
【效率与协作】Computes linkage disequilibrium (r2, D', composite Rogers-Huff r2), prunes correlated variants, clumps GWAS summary statistics to lead SNPs, and defines haplotype blocks with PLINK 1.9/2.0 and scikit-allel. r2 and D' answer different questions - r2 (= chi2/N) is the tagging and GWAS-power currency, D' marks observed recombination and is upward-biased…
bio-workflows-outbreak-pipeline
【数据与研究】Orchestrates genomic-epidemiology outbreak investigation from pathogen isolates to transmission networks, forking bacterial (snippy -> Gubbins recombination-masking -> IQ-TREE -> TreeTime -> TransPhylo) vs viral (Nextstrain/augur), with parallel MLST typing (cgMLST delegated to epidemiological-genomics/pathogen-typing) and AMR surveillance. Use when …
recombinator
【效率与协作】Produce offspring genomes from parent pairs via meiotic recombination, mutation, and clinical evaluation
scenario-ad-variants
【设计与创意】Use when making multiple independent ad or campaign edits from existing footage with Scenario: hook, CTA, copy, end-card, placement, or targeted visual variants. Also for revising one variant or resuming a partially completed batch. Not for a new commercial from a still image, ordinary single-clip grading, or automatic Cartesian combinations.
playwright-skill
【设计与创意】Generates production-grade Playwright automation scripts and E2E tests in TypeScript, JavaScript, Python, Java, or C#. Supports local execution and TestMu AI cloud across 3000+ browser/OS combinations and real mobile devices. Use when the user asks to write Playwright tests, automate browsers, run cross-browser tests, test on real devices, debug flak…