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数据与研究 · SKILL.md

medical-qa

medical-qa

【数据与研究】Medical question answering using structured biomedical knowledge bases and clinical datasets

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name: medical-qa description: Medical question answering using structured biomedical knowledge bases and clinical datasets

Medical Question Answering

Purpose

Answer medical and biomedical questions with evidence-based precision using structured datasets and clinical knowledge bases.

Key Datasets

  • MedQuAD (abachaa/MedQuAD): 47,457 QA pairs from 12 NIH sources (NCI, GARD, GHR, MedlinePlus, NIDDK, NHLBI, NICHD, NIA, NIAMS, NINDS, NIDA, GARD)
  • PubMedQA (qiaojin/PubMedQA): Yes/No/Maybe reasoning from PubMed abstracts

Protocol

  1. Parse the question — Identify medical entities (diseases, drugs, genes, symptoms)
  2. Source identification — Match question type to appropriate NIH source
  3. Evidence retrieval — Search PubMed, clinical guidelines, drug databases
  4. Answer synthesis — Provide answer with confidence level and citations
  5. Verification — Cross-reference with at least 2 independent sources

Question Types

  • Disease/condition: Etiology, diagnosis, prognosis, treatment
  • Drug/treatment: Mechanism, dosage, side effects, interactions
  • Genetic: Gene function, variants, inheritance patterns
  • Prevention: Risk factors, screening, lifestyle modifications

Rules

  • Always cite primary sources (PMID, DOI, or guideline reference)
  • Distinguish between established evidence and emerging research
  • Flag when evidence is limited or conflicting
  • Never provide personalized medical advice
  • Include confidence level: HIGH (multiple RCTs), MODERATE (observational), LOW (case reports)
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