sourmash

MinHash/FracMinHash sketching for alignment-free comparison of genomes and metagenomes. Use for fast all-vs-all genome similarity and ANI estimation across thousands of genomes without alignment, taxonomic classification of metagenomes against GTDB/NCBI reference databases (sourmash gather/tax), and sequencing-cohort QC (contamination or duplicate detection…

Independent GitHub snapshot · Automated classification · Original documentation governs